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PGC-1s may be necessary for exercise-induced mitochondrial biogenesis in adult skeletal muscle. A: schematic of recruited portion of quadriceps (QUAD) during exercise. B: representative electron micrograph images. C: quantification of mitochondrial index from electron micrographs. Data are presented as means ± SE; n = 5 animals per group; 20 images per animal; *P < 0.05 compared with sedentary control as determined by 2-way ANOVA with pairwise comparisons (Tukey adjustment).
