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. 2016 Dec 26;8(12):728–734. doi: 10.4330/wjc.v8.i12.728

Table 2.

List of conventional and newer risk factors in young coronary artery disease discussed in the review

Conventional risk factors Newer risk factors
Age Polymorphisms in CETP gene
Sex Hepatic lipase gene
Hypertension Lipoprotein lipase gene
Diabetes mellitus C-reactive protein gene
Dyslipidaemia Apo A1 gene
Obesity Apo B gene
Smoking Apo E gene
Family history of premature CAD HIF1A gene
Factor 5 leiden
MTHFR gene
Methionine synthase gene
Cocaine use
Lipoprotein-a, Fibrinogen and D-dimer
Decreased serum Wnt
Increased gamma glutamyl transferase
Raised vitamin D2 and D3
Decreased osteocalcin
Hypothyroidism
Systemic lupus erythematosis
Rheumatoid arthritis
HIV patients on HAART
Homocysteinemia
Kawasaki disease in childhood,
Patent foramen ovale
Spontaneous coronary artery dissection

CETP: Cholesterol ester transfer protein; HAART: Highly active anti retroviral therapy; MTHFR: Methylene tetrahydrofolate reductase; HIF1A: Hypoxia inducible factor 1 alpha.