Table 2.
Conventional risk factors | Newer risk factors |
Age | Polymorphisms in CETP gene |
Sex | Hepatic lipase gene |
Hypertension | Lipoprotein lipase gene |
Diabetes mellitus | C-reactive protein gene |
Dyslipidaemia | Apo A1 gene |
Obesity | Apo B gene |
Smoking | Apo E gene |
Family history of premature CAD | HIF1A gene |
Factor 5 leiden | |
MTHFR gene | |
Methionine synthase gene | |
Cocaine use | |
Lipoprotein-a, Fibrinogen and D-dimer | |
Decreased serum Wnt | |
Increased gamma glutamyl transferase | |
Raised vitamin D2 and D3 | |
Decreased osteocalcin | |
Hypothyroidism | |
Systemic lupus erythematosis | |
Rheumatoid arthritis | |
HIV patients on HAART | |
Homocysteinemia | |
Kawasaki disease in childhood, | |
Patent foramen ovale | |
Spontaneous coronary artery dissection |
CETP: Cholesterol ester transfer protein; HAART: Highly active anti retroviral therapy; MTHFR: Methylene tetrahydrofolate reductase; HIF1A: Hypoxia inducible factor 1 alpha.