In Basic Protocol 1, DNA droplets are patterned across a surface with microscale direct writing. In Basic Protocol 2, this DNA is covalently linked to the surface, and the surface is otherwise passivated to cell adhesion. In Basic Protocol 3, cells are functionalized with DNA. In Basic Protocol 4, these cells are assembled into organoids on the surface via DNA hybridization. In Basic Protocol 5, these organoids are released from the surface and into extracellular matrix hydrogel.