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. Author manuscript; available in PMC: 2016 Dec 26.
Published in final edited form as: Curr Genet. 2016 Apr 9;62(4):739–743. doi: 10.1007/s00294-016-0601-7

Fig. 1.

Fig. 1

Condensin-mediated gene interactions and their functions in fission yeast. a Schematic of the TBP-dependent condensin loading. Highly transcribed genes including Pol III genes and Pol II-transcribed housekeeping genes are bound by TBP, which recruits condensin to gene loci. Condensin in turn mediates interactions (green arrows) among highly transcribed genes present on the same chromosomes and centromeres. This genome organization is coupled to the chromosome territory arrangement and gene regulation. b Model explaining how condensinmediated gene interactions with centromeres bolsters the fidelity of chromosome segregation during mitosis.