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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Bioorg Med Chem Lett. 2016 Oct 6;26(22):5573–5579. doi: 10.1016/j.bmcl.2016.09.072

Table 3.

JWS analogs containing cyclic imide groups

graphic file with name nihms824135t16.jpg

Compound R AChE (IC50 µM) BuChE (IC50 µM)
27 graphic file with name nihms824135t17.jpg 11.82 >50
28 graphic file with name nihms824135t18.jpg 33.39 >50
29 graphic file with name nihms824135t19.jpg 3.57 14.46
30 graphic file with name nihms824135t20.jpg 3.34 >50
31 graphic file with name nihms824135t21.jpg 46 >50
32 graphic file with name nihms824135t22.jpg 1.27 7.21
33 graphic file with name nihms824135t23.jpg 0.15 8.01