Table 2.

Univariable and Multivariable Cox Regression Models for the occurrence of the first fall in all participants (n= 449)

	Univariable	Multivariable*
	HR [95% CI] P-value	aHR [95% CI] P-value
Age	1.03 [1.01;1.06] 0.002	1.03 [1.01;1.06] 0.015
Female	1.38 [1.01;1.89] 0.041	1.36 [0.98;1.89] 0.067
Education	1.02 [0.97;1.07] 0.517	1.03 [0.98;1.09] 0.226
ABC score	0.98 [0.97;0.99] <0.001	0.99 [0.98;1.00] 0.040
Presence of FoF	1.75 [1.25;2.43] 0.001	1.38 [0.94;2.00] 0.101
PIGD
Absent	Ref.	Ref.
Mild	1.22 [0.86;1.73] 0.264	1.00 [0.70;1.45] 0.983
Moderate/Severe	2.79 [1.61;4.78] <0.001	2.28 [1.17;4.45] 0.016
Bradykinesia
Absent	Ref.	Ref.
Mild	1.42 [0.88;2.31] 0.155	0.93 [0.54;1.60] 0.795
Moderate/Severe	1.32 [0.85;2.05] 0.210	0.77 [0.45;1.32] 0.343
Rigidity
Absent	Ref.	Ref.
Mild	0.80 [0.42;1.52] 0.488	0.68 [0.35;1.32] 0.251
Moderate/Severe	1.03 [0.73;1.46] 0.855	0.90 [0.60;1.33] 0.581
GHS	1.20 [1.05;1.38] 0.008	1.22 [1.05;1.41] 0.008
Falls in the past 12 months	1.76 [1.24;2.48] 0.001	1.50 [1.04;2.15] 0.028
Gait velocity	0.99 [0.98;1.00] 0.005	1.00 [0.99;1.01] 0.789
GDS-15	1.03 [0.95;1.12] 0.498	0.96 [0.87;1.06] 0.436
RBANS total score	1.00 [0.98;1.01] 0.444	1.00 [0.98;1.01] 0.654

HR: hazard ratio; aHR: adjusted hazard ratio; 95% CI: confidence interval; ABC: Activities-specific Balance Confidence; FoF: fear of falling; EPS: extrapyramidal signs; PIGD: postural instability/gait difficulty; GHS: global health score: GDS: geriatric depression scale; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status.

^*All independent variables (age, gender, education, ABC score, PIGD, bradykinesia, rigidity, GHS, falls in the past 12 months, gait velocity, GDS-15, and RBANS total score) are entered simultaneously into the Cox regression model, except for presence of FoF, where presence of FoF was entered simultaneously into the Cox regression model with age, gender, education, PIGD, bradykinesia, rigidity, GHS, falls in the past 12 months, gait velocity, GDS-15, and RBANS total score.