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. 2016 Dec 27;7:654. doi: 10.3389/fimmu.2016.00654

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Copyright © 2016 Sun, Wang, Ding, Liang, Zhu, Wu, Fan, Li and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The recovery of thymic output measured by CD31⁺ recent thymic emigrants (RTE) (A) and single-joint T-cell receptor excision circles (sjTREC) (B) in peripheral blood within 1 year after the end of chemotherapy in 84 patients. Both the CD31⁺ RTE counts and sjTREC levels decreased to the nadir at the end of treatment and recovered within 1 year of follow-up. Data are shown as means ± SD. P values were assessed by general linear model analysis for repeated-measure data. *P < 0.001 vs. baseline levels; ^#P < 0.05 vs. the nadir at the end of treatment.