Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Zone of Polarizing Activity (ZPA) derived from the hmm−/− limb bud does not have polarizing activity. (A,B,D) In situ hybridization of Ptch2 after ZPA was implanted into the anterior limb bud. (C,E) Fluorescence of the implanted ZPA labeled with DiI is shown. The schematic drawing shows the grafting protocol of ZPA from the donor limb bud (hmm+/− or hmm−/−) to the host limb bud (hmm+/− or hmm−/−). The yellow arrows indicate the position of the implanted ZPA. FLB, forelimb bud.
