Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 27;2:16051. doi: 10.1038/celldisc.2016.51

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Arginine tethers CASTOR1-NTD and CASTOR1-CTD tightly together. (a) Arginine interacts with both the NTD and the CTD of CASTOR1, thus tethering the NTD and the CTD domains tightly together. The other three interfaces between CASTOR1-NTD and -CTD are also shown. (b) The DSC assay demonstrated that arginine promoted tighter folding of CASTOR1, as shown by the increase of its melting temperature (T_m). (c) The DSC assay revealed that the melting temperature of CASTOR2 was not affected by the addition of arginine.