Table 1.
Subject | Age (years) | Sex | Handedness | Pre-op UPDRS III 1 | Post-op UPDRS III 2 | Diagnosis and Predominant Symptom | Clinical DBS Settings Left STN | Clinical DBS Settings Right STN | Bipolar Channels for Behavioral Recording |
---|---|---|---|---|---|---|---|---|---|
1 | 59 | F | R | 37/22 | 35/24/16/13 | PD, bradykinesia | E3⁺, E2−, 3.6 V, 60 µs, 130 Hz | C⁺, E1−, 3.6 V, 60 us, 130 Hz | L: 2/3, R: 0/1 |
2 | 65 | M | R | 48/14 | 49/23/17/16 | PD, rigidity | E1⁺, E2−, 2.6 V, 60 µs, 150 Hz | C⁺, E2−, 2.4 V, 60 us, 150 Hz | L: 2/3, R: 2/3 |
3 | 63 | F | R | 23/6 | 32/25/24/16 | PD, dyskinesias | E3⁺, E2−, 2.4 V, 60 µs, 130 Hz | E3⁺, E2−, 2.5 V, 60 us, 130 Hz | L: 1/2, R: 2/3 |
4 | 71 | M | R | 31/7 | 38/37/21/20 | PD, gait disturbance | E3⁺, E2−, 3.6 V, 60 µs, 130 Hz | E3⁺, E2−, 3.6 V, 60 µs, 130 Hz | L: 2/3, R: 2/3 |
5 | 44 | M | R | 38/20 | 36/16/29/11 | PD, tremor | C⁺, E1−, E2−, 2.9 V, 60 µs, 130 Hz | C⁺, E2−, 3.2 V, 60 µs, 130 Hz | L: 1/2, R: 2/3 |
6 | 62 | M | L | 31/20 | 24/16/21/14 | PD, tremor | C⁺, E1−, 2.6 V, 60 µs, 130 Hz | C⁺, E1−, 3.9 V, 70 µs, 135 Hz | L: 1/2, R: 2/3 |
7 | 68 | M | R | 67/40 | -/-/-/- | PD, bradykinesia | C⁺, E1−, 2.2 V, 60 µs, 130 Hz | C⁺, E2−, 2.0 V, 60 µs, 130 Hz | L: 2/3, R: 2/3 |
1 Pre-op UPDRS III listed in order of Medication off/Medication on; 2 Post-op UPDRS III listed in order of Medication off-DBS off/Medication off-DBS on/Medication on-DBS off/Medication on-DBS on. PD, Parkinson’s disease. UPDRS, unified Parkinson’s disease rating scale. STN, subthalamic nucleus. M, male. F, female. L, left. R, right.