Fig. 2.

Reduction of degeneration and chronic inflammation in HRG-treated mdx mice. (a) H&E staining of low- and high-power fields (Upper and Lower) of control mdx TA muscle (from two representative mice) showing multiple foci of muscle degeneration and infiltration with cellular exudate (black arrows) and phagocytosis (white arrows) compared with HRG mdx TA muscle (from two representative mice), consistent with reduction of necrotic foci (b), CNFs (c), and serum CK (d) in treated mdx mice. (Scale bar, 50 μm.)