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. 2016 Dec 5;113(51):14633–14638. doi: 10.1073/pnas.1625010114

Fig. 4.

Fig. 4.

Specific PSA detection in high–ionic-strength solutions. (A) The 300 nM PSA responses from 1:2 PEG:ETA-, pure aptamer-, and 1:2 PEG:aptamer-modified graphene FET devices. (B) A device with 1:2 PEG:aptamer modification shows consistent response to 100 nM PSA before and after 6 M guanidinium chloride regeneration for 10 min. (C) A device (distinct from B) with 1:2 PEG:aptamer modification first shows consistent response to 100 nM PSA before and after regeneration, and then shows a weaker and reversible response to 100 nM CEA. All experiments were carried out in pH 7.4 1× PBS containing 2 mM Mg2+.