Soil urban parks of NYC, an urban area of 10 million inhabitants, were found to contain biosynthetic genes clusters involved in the biosynthesis of many widely used drugs, revealing an untapped reservoir of new therapeutics. Images courtesy of The Noun Project under public domain license or Creative Commons (CC 3.0); DNA courtesy of Warslab, Freedom Tower courtesy of Chris McDonnell, city plant courtesy of GRACE Communications Foundation and Mother Jones, New York city courtesy of Raf Verbraeken, Statue of Liberty courtesy of Shashank Singh, park bench courtesy of Roma, and pills courtesy of Tonielle Purdy.