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. 2016 Nov 25;17(12):1980. doi: 10.3390/ijms17121980

Figure 2.

Figure 2

SOD-1 expression within the arterial wall of PAIS-susceptible vs. non-susceptible artery of P1 rat pups from the S group: (a) unbalanced expression of SOD-1 between intima and media of intra- but not extra-cranial arteries (labeling score; see method section and Figure S1); and (b) SOD-1 staining by IF (white arrowheads) in PAIS-susceptible (icICA) vs. non-susceptible (ecICA) arteries. Data are presented as mean ± standard error of the mean (SEM). * p < 0.05, ** p < 0.01, Mann–Whitney test. n = 5–9 arteries from 4–5 animals per condition. Scale bar = 7 µm. Abbreviations: ACA, anterior cerebral artery; BA, basilar artery; ec, extra-cranial; ic, intra-cranial; ICA, internal carotid artery; MCA, middle cerebral artery; PCA, posterior cerebral artery; S, saline; SOD-1, superoxide dismutase-1.