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. 2016 Nov 26;17(12):1984. doi: 10.3390/ijms17121984

Figure 1.

Figure 1

Gene Expression Omnibus (GEO) profile assessment of Ddit4/DDIT4 responses to biological and stress conditions within epithelial cells. (1.5 column) (A) For all DataSets presented in this figure, the graphs represent Ddit4/DDIT4 transcript levels. DataSet GDS2637 shows that Ddit4 was not induced after 56FE ion irradiation within a rat keratinocyte cell line; (B) DataSet GDS3766 shows that NF-κB activation by IKKβ overexpression in mouse dorsal skin resulted in increased Ddit4 levels; (C) DataSet GDS3211 reports that periodontal pathogen infection of a human gingival epithelial cell line with Aggregatibacter actinomycetemcomitans led to DDIT4 induction; (D) DataSet GDS4608 shows that upon injury of human epidermal cells, DDIT4 transcript levels were increased compared to uninjured samples; (E) DataSet GDS687 shows that differentiation of keratinocyte stem cells upon mesenchymal-epithelial interactions resulted in decreased DDIT4 expression over time. All DataSets can be accessed at: http://www.ncbi.nlm.nih.gov/geoprofiles.