Table 1.

Association between circulating tumor cells (CTC) and baseline characteristics.

Variables	N	CTC/7.5 mL		p-Value
		Mean	Range
CTC count at base	60	8	0–184	0.042
PSA (ng/mL)
<30	30	2	0–3	0.021
≥30	30	15	0–184
Biopsy Gleason score
7–8	29	2	0–6	0.003
9–10	31	19	0–184
EOD
1–2	39	1	0–14	0.034
3–4	21	23	0–184
Hemoglobin (g/dL)
<11.5	35	18	0–184	0.059
≥11.5	25	5	0–13
Serum albumin (g/dL)
<3.7	28	19	0–184	0.059
≥3.7	22	4	0–12
Alkaline phosphatase (IU/L)
<313	21	3	0–34	0.002
≥313	39	18	0–184
Lactate dehydrogenase (IU/L)
<226	26	2	0–18	0.066
≥226	34	19	0–184
Disease involvement
Only bone	42	6	0–45	0.014
Bone plus node	18	15	0–184

CTC median and range are expressed as cells per 7.5 mL of blood. The extent of bone metastasis was classified by the extent of disease (EOD) grade.