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. 2016 Dec 1;17(12):2011. doi: 10.3390/ijms17122011

Figure 2.

Figure 2

Dose- and time-dependent viability of (A) HRT-18 cells and (B) Caco-2 cells. Cells were seeded in 96-well microplates and treated with 1.25, 2.50, 5.00, 10.00 and 20.00 µM sorafenib. Viability was analyzed using WST-1 assay after 24, 48 and 72 h sorafenib treatment; data points represent mean values ± SEM of two independent experiments. ‘DMSO’ indicates samples treated with the solvent only (highest concentration). *, ** indicate values significantly (p < 0.05) or highly significantly (p < 0.01) different from the untreated control (UTC), respectively (two-sided, unpaired t-test).