Table 2.

Pathway analyses of differentially-expressed miRNA-related signaling pathways and example genes after 6 and 18 h of tensile stress stimulation.

Signaling Pathway	Example Genes
6 vs. 0 h
MAPK signaling pathway	MAPK1, EGFR, FGF1, FGF10, TGFβ2, TGFβR1
T cell receptor signaling pathway	MAPK1, KRAS, NRAS, IL5, IL2, IL10, SOS1, SOS2
Chemokine signaling pathway	MAPK1, KRAS, NRAS, SOS1, GRB2, PTK2, PIK3R1
Pathways in cancer	SMAD4, RUNX1, TGFβ2, TGFβR1, IGF1R, IGF1, BMP2
Wnt signaling pathway	DKK2, TCF3, APC, DKK3, RUNX2
TGFβ/BMP-Smad signaling pathway	SMAD4, TGFβ2, TGFβR1, BMP2, BMP3
18 vs. 0 h
MAPK signaling pathway	FGFR1, FGFR2, FGF13, FGF5, TGFβR2, MAP3K1
Pathways in cancer	FGFR1, FGFR2, FGF5, SMAD4, TGFβR2, IGF1, RUNX2
Cytokine-cytokine receptor interaction	PDGFRβ, TGFBβ2, IL1, IL12β, IL6
Wnt signaling pathway	RHOA, APC, RUNX2, SMAD4, FZD4, FZD6, LRP6, DKK2
TGFβ/BMP-Smad signaling pathway	SMAD4, TGFβ2, TGFβR1, BMP2, BMP3