Table 2.
Human epidermal growth factor receptor 2 (HER2) expression in thyroid cancer tissue *.
| HER2 Status | FTC (n = 45) | PTC (n = 45) | p |
|---|---|---|---|
| IHC Negative/low (0, 1+) | 12 (26.6%) | 30 (66.6%) | 0.020 |
| Equivocal (2+) | 15 | 7 | |
| Positive (3+) | 18 | 8 | |
| IHC/FISH | |||
| Positive cases | |||
| (3+ and amplified) | 20 (44.4%) | 8 (17.7%) | 0.046 |
* HER2 status has been assessed by using immunohistochemistry (IHC) to detect protein expression. Fluorescence in situ hybridization (FISH) was also performed in cases that tested 2+ at IHC, as specified in the Materials and Methods section to detect gene amplification.