Table 2.
Association analysis of ELMO3 expression with clinicopathological parameters of CRC patients.
| Clinical Parameter | ELMO3 Immunoreactivity Score | N | p-Value | |||
|---|---|---|---|---|---|---|
| − | + | ++ | +++ | |||
| Gender | 0.883 † | |||||
| Male | 5 | 5 | 4 | 13 | 27 | |
| Female | 0 | 4 | 8 | 6 | 18 | |
| Age (years) | ||||||
| ≤60 | 3 | 6 | 9 | 7 | 25 | 0.094 † |
| >60 | 2 | 3 | 3 | 12 | 20 | |
| Tumor size (cm) | 0.007 † | |||||
| ≤4.0 | 4 | 8 | 7 | 7 | 26 | |
| >4.0 | 1 | 1 | 5 | 12 | 19 | |
| Differentiation | 0.001 ‡ | |||||
| High | 4 | 3 | 1 | 0 | 8 | |
| Moderate | 1 | 5 | 10 | 12 | 28 | |
| Poor | 0 | 1 | 1 | 7 | 9 | |
| Depth of invasion | 0.009 † | |||||
| T1 + T2 | 4 | 1 | 4 | 1 | 10 | |
| T3 + T4 | 1 | 8 | 8 | 18 | 35 | |
| Lymph node metastasis | 0.003 † | |||||
| No | 5 | 9 | 9 | 10 | 33 | |
| Yes | 0 | 0 | 3 | 9 | 12 | |
| Distant metastasis | 0.013 † | |||||
| No | 5 | 9 | 12 | 14 | 40 | |
| Yes | 0 | 0 | 0 | 5 | 5 | |
| TNM classification | 0.000 † | |||||
| I + II | 5 | 9 | 9 | 7 | ||
| III + IV | 0 | 0 | 3 | 11 | ||
| Lymph node positive number | 0.003 † | |||||
| <1 | 5 | 9 | 9 | 10 | 33 | |
| ≥1 | 0 | 0 | 3 | 9 | 12 | |
† statistical analysis was performed by the Mann–Whitney U test; ‡ statistical analysis was performed by Kruskal–Wallis H test.