Table 5.

Ulcerogenic activity of synthesized mutual prodrugs (5a–c) and Dexibuprofen.

Serial. No.	Compounds	Ulcer Index (Mean±SEM)
Control group	CMC *	0.37 ± 0.37
1	Dexibuprofen	2.89 ± 0.63
2	5a	1.55 ± 0.09 **
3	5b	1.34 ± 0.06 **
4	5c	1.61 ± 0.58 *

CMC * = Carboxymethyl cellulose, Values are expressed as Mean ± SEM, (n = 6) by one way ANOVA (followed by Tukey) test, Significant at * = p < 0.05, ** = p < 0.01 vs. Dexibuprofen.