Fig. 6.
The protective effects of in I/R. (a) The effect of
(10 or 100 μM; n = 6 each) compared with saline control (n = 8) on left ventricular developed pressure (LVDP) during I/R. The effect of
(10 μM) was reversed by the NO• scavenger carboxy-PTIO (
+ C-PTIO, n = 6); carboxy-PTIO alone (C-PTIO, 30 μM; n = 6) had no significant effect compared with saline control. (b) The effect of
on infarct size compared with saline control in the absence and presence of carboxy-PTIO. **, P < 0.01 compared with saline control; ##, P < 0.01 compared with carboxy-PTIO +
.