Table 5.

Effects of isoflavones on the decrease in hot flash frequency according to the genistein content of the supplement ¹.

Genistein Dose (mg/Day)	Number of Trials	n	Fixed Effects Model			Random Effects Model
			Percent	95% CI	p Value	Percent	95% CI	p Value
≤18.8	7	596	−12.47	−17.34, −7.60	<0.00001	Same as Fixed Effects Model
>18.8	6	600	−26.50	−33.11, −19.90	<0.00001	−29.13	−43.09, −15.17	<0.0001
Test for Subgroup Difference			p = 0.0008			p = 0.03

¹ Source: reference [305].