Figure 6. Effect of exendin-4 (Ex4) on lipopolysaccharide (LPS)-activated NF-κB pathway in mouse peritoneal macrophage. Mouse peritoneal macrophages were treated with LPS or a combination of LPS and Ex4 for 30 min. Western blot image (A) and quantification (B) of basal protein and phosphorylation levels of IκBα. Western blot image (C) and quantification (D) of NF-κB protein level in nuclei. TCL: total cell lysate. The results are representative of three independent experiments. Data are reported as means±SD. ***P<0.001 (ANOVA).