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. 2016 Oct 7;56(1):156–164. doi: 10.1093/rheumatology/kew355

Fig. 5.

Fig. 5

Racemized Asx content in PBS and insoluble extract alkaptonuric cartilage vs OA and non-OA

Graphs showing the amount of racemized Asx (D form) as a proportion of non-racemized Asp (L form) represented by the D/D+L ratio in AKU, OA and non-OA cartilage specimens. (A) Asx ratio (D/D+L) in PBS extract of all samples: both hips and knees from AKU (n = 6), OA (n = 12) and non-OA (n = 6) independent cartilage specimens. (B) Asx ratio (D/D+L) in PBS extract from hip-only samples from AKU (n = 4), OA (n = 7) and non-OA (n = 5) independent cartilage specimens. (C) Asx ratio (D/D+L) in insoluble extract of all samples: both hips and knees from AKU (n = 6), OA (n = 12) and non-OA (n = 6) independent cartilage specimens, (D) Asx ratio (D/D+L) in insoluble extract from hip-only samples from AKU (n = 4), OA (n = 7) and non-OA (n = 5) for independent cartilage specimens. Error bars represent the mean of the n in each group ± 95% CI. AKU: alkaptonuria; racemized Asx: aspartate and asparagine; Asp: aspartate; D: dextrorotary (d-isomer); L: levorotary (l-isomer).