Table 3.
Demographic and clinical characteristics of patients with stage III uterine carcinosarcoma by treatment received.
| Observation (N = 16) | CT only (N = 34) | RT only (N = 20) | CT + RT (N = 37) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Variable | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | p-value |
| Age | 16 | 70.9 (11.1) | 34 | 67.3 (9.6) | 20 | 68.0 (9.1) | 37 | 65.0 (10.5) | 0.25 |
| Year of diagnosis | 16 | 2005.7 (3.7) | 34 | 2006.1 (5.0) | 20 | 2004.5 (4.6) | 37 | 2006.7 (3.9) | 0.33 |
| Body mass index (BMI) | 13 | 32.0 (6.5) | 30 | 32.1 (7.5) | 18 | 32.2 (8.1) | 33 | 30.4 (6.0) | 0.73 |
| Parity | 15 | 3.5 (3.2) | 33 | 2.6 (1.8) | 18 | 2.6 (1.6) | 36 | 2.8 (1.9) | 0.57 |
| N | % | N | % | N | % | N | % | p-value | |
|
| |||||||||
| Race | 0.01 | ||||||||
| White | 4 | 25.0 | 20 | 58.8 | 7 | 35.0 | 25 | 69.4 | |
| Black | 12 | 75.0 | 14 | 41.2 | 13 | 65.0 | 11 | 30.6 | |
| Missing | 0 | 0 | 0 | 1 | |||||
| Smoking | 0.19 | ||||||||
| Yes | 6 | 40.0 | 4 | 12.1 | 4 | 22.2 | 7 | 20.0 | |
| No | 9 | 60.0 | 29 | 87.9 | 14 | 77.8 | 28 | 80.0 | |
| Missing | 1 | 1 | 2 | 2 | |||||
| Clinic site | 0.13 | ||||||||
| 1 | 7 | 43.8 | 12 | 35.3 | 3 | 15.0 | 18 | 48.7 | |
| 2 | 2 | 12.5 | 6 | 17.7 | 2 | 10.0 | 7 | 18.9 | |
| 3 | 6 | 37.5 | 11 | 32.4 | 14 | 70.0 | 9 | 24.3 | |
| 4 | 1 | 6.3 | 5 | 14.7 | 1 | 5.0 | 3 | 8.1 | |
| Cancer history | 0.78 | ||||||||
| Yes | 3 | 18.8 | 5 | 14.7 | 5 | 25.0 | 6 | 16.2 | |
| No | 13 | 81.3 | 29 | 85.3 | 15 | 75.0 | 31 | 83.8 | |
| Radiation history | 0.84 | ||||||||
| Yes | 1 | 6.3 | 3 | 8.8 | 3 | 15.8 | 4 | 10.8 | |
| No | 15 | 93.8 | 31 | 91.2 | 16 | 84.2 | 33 | 89.2 | |
| Missing | 0 | 0 | 1 | 0 | |||||
| LSVI | 0.02 | ||||||||
| Yes | 14 | 87.5 | 27 | 87.1 | 8 | 47.1 | 26 | 74.3 | |
| No | 2 | 12.5 | 4 | 12.9 | 9 | 52.9 | 9 | 25.7 | |
| Missing | 0 | 3 | 3 | 2 | |||||
| Stage | 0.64 | ||||||||
| IIIA | 6 | 37.5 | 11 | 32.4 | 5 | 25.0 | 8 | 21.6 | |
| IIIB | 1 | 6.3 | 1 | 2.9 | 3 | 15.0 | 4 | 10.8 | |
| IIIC | 9 | 56.3 | 22 | 64.7 | 12 | 60.0 | 25 | 67.6 | |
| Positive nodes | 0.56 | ||||||||
| Yes | 8 | 53.3 | 14 | 45.2 | 8 | 42.1 | 14 | 37.8 | |
| No | 7 | 46.7 | 17 | 54.8 | 11 | 57.9 | 23 | 62.2 | |
| Missing | 1 | 3 | 1 | 0 | |||||
| Residual disease | 0.04 | ||||||||
| Yes | 4 | 25.0 | 6 | 18.8 | 0 | 0.0 | 2 | 5.7 | |
| No | 12 | 75.0 | 26 | 81.3 | 17 | 100.0 | 33 | 94.3 | |
| Missing | 0 | 2 | 3 | 2 | |||||
| Cervix + disease | 0.12 | ||||||||
| No | 4 | 25.0 | 21 | 61.8 | 9 | 50.0 | 19 | 51.4 | |
| Yes | 12 | 75.0 | 13 | 38.2 | 9 | 50.0 | 18 | 48.7 | |
| Missing | 0 | 0 | 2 | 0 | |||||
| Ovaries + disease | 0.02 | ||||||||
| No | 8 | 50.0 | 18 | 52.9 | 15 | 88.2 | 27 | 75.0 | |
| Yes | 8 | 50.0 | 16 | 47.1 | 2 | 11.8 | 9 | 25.0 | |
| Missing | 0 | 0 | 3 | 1 | |||||
| Uterine serosa + disease | 0.11 | ||||||||
| No | 7 | 43.8 | 26 | 76.5 | 14 | 77.8 | 26 | 72.2 | |
| Yes | 9 | 56.3 | 8 | 23.5 | 4 | 22.2 | 10 | 27.8 | |
| Missing | 0 | 0 | 2 | 1 | |||||
| Vagina + disease | 0.10 | ||||||||
| No | 13 | 81.3 | 32 | 94.1 | 13 | 76.5 | 34 | 94.4 | |
| Yes | 3 | 18.8 | 2 | 5.9 | 4 | 23.5 | 2 | 5.6 | |
| Missing | 0 | 0 | 3 | 1 | |||||
| Recurrence outcomes | |||||||||
| Recurrence | 0.36 | ||||||||
| Yes | 9 | 64.3 | 21 | 67.7 | 11 | 55.0 | 17 | 47.2 | |
| No | 5 | 35.7 | 10 | 32.3 | 9 | 45.0 | 19 | 52.8 | |
| Unknown | 2 | 3 | 1 | 1 | |||||
| Site of initial documented recurrence | 0.001 | ||||||||
| Vaginal only | 6 | 66.7 | 1 | 4.8 | 2 | 18.2 | 2 | 12.5 | |
| Other pelvic | 1 | 11.1 | 2 | 9.5 | 0 | 0.0 | 5 | 31.3 | |
| Extra pelvic/multiple | 2 | 22.2 | 18 | 85.7 | 9 | 81.8 | 9 | 56.3 | |