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. 2016 Dec 27;13(12):e1002204. doi: 10.1371/journal.pmed.1002204

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© 2016 Savas et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — Treatment history (A) and subclonal structure (B and C) for TN1, inferred using PyClone and Schism. Pre- and postmortem samples are shown. FEC: 5-fluorouracil, epirubicin, cyclophosphamide; TCH: docetaxel, carboplatin, trastuzumab; AURKA: aurora kinase; P1: multiple samples from archival breast primary (post-neoadjuvant chemotherapy); M1: liver core biopsy; A1: left upper lobe metastasis; A2: left liver lobe metastasis; A3, A4, A5: left lung metastases; A6: right liver lobe metastasis.