Table 2.
Association of AZGP1 expression with clinicopathologic features of patients with esophageal squamous cell carcinoma (n=215)
| Clinicopathologic features | n | AZGP1 expression, n (%)
|
χ2 | P-value | |
|---|---|---|---|---|---|
| Downregulation | Normal expression | ||||
| Age (years) | 3.367 | 0.067 | |||
| ≤60 | 125 | 62 (49.6) | 63 (50.4) | ||
| >60 | 90 | 56 (62.2) | 34 (37.8) | ||
| Gender | 0.482 | 0.487 | |||
| Male | 123 | 65 (52.8) | 58 (47.2) | ||
| Female | 92 | 53 (57.6) | 39 (42.4) | ||
| Location | 3.512 | 0.173 | |||
| Upper | 43 | 28 (65.1) | 15 (34.9) | ||
| Middle | 108 | 53 (49.1) | 55 (50.9) | ||
| Lower | 64 | 37 (57.8) | 27 (42.2) | ||
| Tumor cell differentiation | 0.654 | 0.721 | |||
| Well | 31 | 15 (48.4) | 16 (51.6) | ||
| Moderate | 135 | 75 (55.6) | 60 (44.4) | ||
| Poor | 49 | 28 (57.1) | 21 (42.9) | ||
| T category | 5.992 | 0.112 | |||
| T1 | 14 | 4 (28.6) | 10 (71.4) | ||
| T2 | 43 | 23 (53.5) | 20 (46.5) | ||
| T3 | 78 | 41 (52.6) | 37 (47.4) | ||
| T4 | 80 | 50 (62.5) | 30 (37.5) | ||
| N category | 4.442 | 0.035* | |||
| N0 | 116 | 56 (48.3) | 60 (51.7) | ||
| N1 | 99 | 62 (62.6) | 37 (37.4) | ||
| TNM stage | 8.080 | 0.018* | |||
| I | 11 | 2 (18.2) | 9 (81.8) | ||
| II | 119 | 63 (52.9) | 56 (47.1) | ||
| III | 85 | 53 (62.4) | 32 (37.6) | ||
| General classification | 0.590 | 0.899 | |||
| Medullary type | 117 | 67 (57.3) | 50 (42.7) | ||
| Ulcerative type | 54 | 28 (51.9) | 26 (48.1) | ||
| Sclerotic type | 21 | 11 (52.4) | 10 (47.6) | ||
| Mushroom type | 23 | 12 (52.2) | 11 (47.8) | ||
Notes:
*
Statistically significant.