Table 1.

One-compartment pharmacokinetic parameters for R- and S-metoprolol for young men and women.

	S-Metoprolol		R-Metoprolol
	Female	Male	Female	Male
V (L): Volume of distribution	34.9	55.3	38.1	63.9
CL (L/h): Clearance Rate	101	253	120	316
Ka (h−1): Absorption rate constant	0.161	0.241	0.165	0.234
Tlag (h): Absorption lag time	0.38	0.67	0.39	0.59