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. 2016 May 29;7(28):43062–43075. doi: 10.18632/oncotarget.9657

Figure 4. A. Comet assay showing tail formation in A673 cells up on treatment with BO-1055 for 3h.

Figure 4

B. Olive tail moment (micrometers) in hMSC, cord blood CD34+ hematopoietic progenitor cells and A673 cells in 3 conditions-untreated, exposed to 8Gy radiation, treatment with BO-1055 at 5μM conc. C. Induction of γH2AX in different cells treated with increasing concentration of BO-1055. D. Western blot showing induction of proteins involved in DNA damage repair in two sensitive cell lines- A673 (Ewing sarcoma) and H526 (small cell lung cancer) and a resistant cell line- U20S (osteosarcoma) treated with 2μM concentration of B0-1055 for 6h and 24h.