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. 2016 Apr 26;7(28):43124–43149. doi: 10.18632/oncotarget.8988

Figure 1. Alterations of WP genes in TNBC and basal-like BC subtypes.

Figure 1

A. Oncoprints showing alterations in WP associated CTNNB1, APC and DVL1 in Breast Invasive Carcinoma (upper panel) and Breast Invasive Carcinoma; PAM50 Basal-like (lower panel). The patient selected were, (1) Breast Invasive Carcinoma; TCGA 2012 (825 patients/825 samples), and (2) Breast Invasive Carcinoma (TCGA 2012); PAM50 Basal (81 patients/81 samples). B. Oncoprints showing alterations in CTNNB1, APC and DVL1 in PAM50 Basal-like brca/tcga/pub2015 (upper panel) and triple-negative breast tumors brca/tcga/pub2015 (lower panel). The oncoprints are generated using 107 patients/107 samples for PAM50 Basal-like and 82 patients/82 samples for Triple-negative breast tumors. Advanced cancer genomic data visualization is obtained with the help of “The Onco Query Language (OQL)”. Oncoprints (different levels of zoom) have been generated using cBioPortal. Individual genes are represented as rows, and individual cases or patients are represented as columns. Protein level obtained from IHC staining (cBioPortal).