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. 2016 Jun 2;7(28):43534–43545. doi: 10.18632/oncotarget.9780

Figure 3. FOXN3 suppresses HCC tumorigenesis in vivo.

Figure 3

(A) SMMC-7721 cells stably transfected with FOXN3 were subcutaneously injected into nude mice; empty vectors were used as a control. After 7 weeks, the tumors were removed from the nude mice. (B) The weight of the liver tumors in (A). (C) Western blot analysis of FOXN3 expression in the samples in (A). (D) qPCR analysis of FOXN3 expression in the samples in (A). (E) MHCC-97L cells stably transfected with FOXN3 were orthotopically injected into the livers of nude mice; empty vectors were used as a control. After 4 weeks, the tumors were removed from the nude mice. (F) The weight of the liver tumors in (E). (G) Western blot analysis of FOXN3 expression in the samples in (E). (H) qPCR analysis of FOXN3 expression in the samples in (E). *P < 0.05, **P < 0.01.