Figure 9. Schematic illustration of roles of ERK1/2, p38, JNK1/2 and Notch3 in basal and TGF-β1-induced myofibroblast differentiation.

ECM, extracellular matrix; ROS, reactive oxygen species; →, lead to/activate; , inhibit. Line thickness indicates the extent of impact. Superscripts indicate the level or activation status.