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. 2016 Jun 11;7(28):43974–43988. doi: 10.18632/oncotarget.9949

Figure 1. Regardless mutation status, the plasma levels of IL-1β, TNF-α and TIMP-1 are increased in MF patients.

Figure 1

IL-1β (A), TNF-α (B) and TIMP-1 (C) plasma levels were measured by ELISA in MF patients. (n = 26; JAK2V617F positive n =16; CALR positive n = 10) and healthy controls (n = 15). Compared with controls, cytokines plasma levels were significantly increased in MF patients. Of note, there was no significant difference between JAK2V617F or CALR mutated patients. All data are presented as mean ± SEM (**p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001).