Table 2. Univariate analysis assessing the factors related to the methylation high.

Variables	Odds ratio (95% confidence interval)	P value
Age	1.04 (1.00-1.07)	0.04
Gender (male)	0.88 (0.40-1.96)	0.76
H. pylori positive	34.3 (4.44-264.62)	0.0007
Gastric ulcer	2.01 (0.67-6.04)	0.21
Duodenal ulcer	3.70 (1.04-13.20)	0.04
Active gastritis	1.47 (0.58-3.68)	0.41
Atrophic gastritis	4.67 (2.02-10.80)	0.0003
Telomere shortening	1.96 (1.35-2.84)	0.0004
LINE1 methylation	1.09 (0.94-1.27)	0.24

^*Methylation high, mean Z score of methylation>0.3.