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. 2016 Jun 1;7(28):44013–44022. doi: 10.18632/oncotarget.9768

Figure 2. MDM2 knockdown and apoptosis induction in NSCLC PC9 cells.

Figure 2

A. MDM2 mRNA expressions in PC9 cells treated with G5-DAT62/siScr, G5-DAT62/siMDM2 (N/P = 100 and 120), and Lipo 2000/siMDM2 determined by quantitative real time PCR. * p < 0.05 and ***p < 0.001. B. Representative cleaved caspase-8, p53 and Rb protein expressions in the transfected PC9 cells determined by western blot analysis. C. Apoptosis analysis of the transfected PC9 cells by an Annexin V-FITC/PI double staining assay.