Table 2. Stratified analyses of the combined variant alleles and HCC susceptibility.
| Variables | HCC susceptibility (0 / 1-3 / 4-6) | |||
|---|---|---|---|---|
| HCC patients | HBV persistent carriers | OR (95% CI) | P* | |
| Age | ||||
| ≤53 | 476/351/42 | 510/313/34 | 1.04 (0.86-1.25) | 0.252 |
| >53 | 308/202/33 | 461/201/27 | 1.23 (0.99-1.53) | |
| Gender | ||||
| Male | 644/440/54 | 770/426/49 | 1.06 (0.91-1.25) | 0.133 |
| Female | 140/113/21 | 201/88/12 | 1.39 (1.01-1.90) | |
| HBV Genotype | ||||
| B-related† | 174/88/3 | 645/317/33 | 0.89 (0.69-1.15) | 0.029 |
| Non-B¶ | 594/446/72 | 317/183/27 | 1.26 (1.05-1.50) | |
Note: The logistic regression analyses were adjusted for age, gender and HBV genotype (excluding the stratified factor in each stratum) in the additive genetic model.
*
P-value for the heterogeneity test.
†
B-related genotypes including B and BC.
¶
Non-B genotypes including C and D.