Table 3. Correlations between SII and clinicopathological characteristics (n=445).
| Variables | SII | p-value | ||
|---|---|---|---|---|
| <572 | ≥572 | |||
| No. of patients | 335 | 110 | ||
| Age (y) | ≤50 | 94 | 34 | 0.567 |
| >50 | 241 | 76 | ||
| Sex | Male | 217 | 79 | 0.175 |
| Female | 118 | 31 | ||
| Pathological TNM stage | StageI (IA and IB) | 108 | 9 | 2.10E-06 |
| StageII (IIA and IIB) | 77 | 28 | ||
| StageIII (IIIA and IIIB) | 150 | 73 | ||
| T stage | T1 | 87 | 7 | 2.66E-05 |
| T2 | 46 | 10 | ||
| T3 | 33 | 16 | ||
| T4a | 169 | 77 | ||
| N stage | N0 | 157 | 27 | 2.15E-04 |
| N1 | 47 | 18 | ||
| N2 | 56 | 22 | ||
| N3 | 75 | 43 | ||
| Lymph node metastasis | no | 157 | 27 | 3.72E-05 |
| yes | 178 | 83 | ||
| Tumor differentiation | G1 | 33 | 4 | 0.227 |
| G2 | 138 | 51 | ||
| G3 | 135 | 48 | ||
| Mucinous adenocarcinoma | 13 | 2 | ||
| Signet ring cell carcinoma | 16 | 5 | ||
| TYMP expression* | negative | 188 | 50 | 0.046 |
| positive | 140 | 58 | ||
SII, systemic immune-inflammation index; TYMP, thymidine phosphorylase;
*
TYMP expression and SII was avalible in 436 patients.