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. 2016 Jun 15;7(28):44395–44405. doi: 10.18632/oncotarget.10054

Table 3. Univariate analysis for associations of TILs with DFS, DDFS and OS in TNBCs.

Variables DFS DDFS OS
HR 95% CI P-value HR 95% CI P-value HR 95% CI P-value
sTILs(per 10% increase) 0.97 0.95–0.99 0.001* 0.96 0.94–0.98 0.001* 0.96 0.94–0.99 0.003*
iTILs(per 10% increase) 0.98 0.91–1.05 0.53 0.98 0.91–1.06 0.57 1.02 0.95–1.10 0.61
LPBC v No LPBC 0.25 0.04–1.83 0.17 0.05 0.01–6.03 0.22 0.05 0.03–13.6 0.29
sTILs ≤ 20% v sTILs > 20% 0.24 0.10–0.60 0.002* 0.16 0.05–0.51 0.002* 0.23 0.07–0.73 0.01*

Abbreviations: TNBCs: triple-negative breast cancers; sTILs, stromal tumor-infiltrating lymphocytes; iTILs, intratumoral tumor-infiltrating lymphocytes; LPBC, lymphocyte-predominant breast cancer; DFS, disease-free survival; DDFS, distant disease-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval.

*

The P value is significant.