Table 2. Sphere-forming efficiency of sorted PC3 and DU145 cells sorted based on extracellular Trop2 expression level, as calculated using the ELDA webtool.
| Cell population | Sphere-forming frequency of androgen-independent cells | |
|---|---|---|
| Estimate | Confidence Interval | |
| PC3 - Ungated | 1/51.5# | 1/43.8 – 1/60.4 |
| PC3 - Trop2high | 1/18.2*# | 1/15.4 – 1/21.4 |
| PC3 - Trop2low | 1/127.7* | 1/104.5 – 1/156.0 |
| DU145 - Ungated | 1/25.2 | 1/14.5 – 1.39.5 |
| DU145 - Trop2high | 1/5.6*# | 1/3.3 – 1/9.4 |
| DU145 - Trop2low | 1/18.2 | 1/11.1 – 1/30.1 |
*
significantly different from ungated population (P<0.0001);
#
significantly different from Trop2low cells (P<0.0001, Pearson Chi-square test).