Table 3. spheroid-forming efficiency of sorted PC3 cells according to their surface Trop2 expression and ALDH activity, as calculated using the ELDA webtool.
| Cell population | Sphere-forming frequency | |
|---|---|---|
| Estimate | Confidence Interval | |
| Ungated | 1/62.6 | 1/49.5 - 1/79.1 |
| ALDHhighTrop2high | 1/16.8* | 1/13.3 – 1/21.2 |
| ALDHhighTrop2medium | 1/129.3 | 1/97.3 – 1/171.7 |
| ALDHlowTrop2high | 1/13.3* | 1/10.5 – 1/16.9 |
| ALDHlowTrop2medium | 1/74.8 | 1/58.7 – 1/95.3 |
| ALDHlowTrop2low | 1/182.0 | 1/131.9 – 1/251.2 |
*
significantly different from Trop2medium and Trop2low populations (P<0.0001, Pearson Chi-square test).