Table 3. Survival analyses stratified by clinicopathologic characteristics and treatment parameters in different countries.
China (N = 1105) | Korea (N = 4877) | P value† | |||
---|---|---|---|---|---|
N | 5-y OSR (%) | N | 5-y OSR (%) | ||
Gender | |||||
Female | 324 | 56.3 | 1700 | 83.3 | < 0.001 |
Male | 781 | 53.4 | 3177 | 80.4 | < 0.001 |
Age (yrs) | |||||
< 60 | 618 | 55.4 | 2643 | 84.5 | < 0.001 |
≥ 60 | 487 | 52.9 | 2234 | 77.6 | < 0.001 |
Longitudinal Tumor location | |||||
Upper third | 280 | 43.7 | 670 | 76.9 | < 0.001 |
Middle third | 140 | 54.4 | 1334 | 82.4 | < 0.001 |
Lower third | 661 | 59.9 | 2861 | 82.1 | < 0.001 |
Whole stomach | 24 | 23.4 | 12 | 43.7 | 0.155 |
Differentiation | |||||
G1 | 11 | 90.0 | 645 | 92.0 | 0.814 |
G2 | 148 | 62.7 | 1387 | 81.0 | < 0.001 |
G3 | 946 | 52.6 | 2845 | 79.1 | < 0.001 |
Tumor size (cm) | |||||
≤ 2 | 157 | 83.8 | 1660 | 94.7 | < 0.001 |
~ 5.0 | 523 | 59.2 | 2232 | 83.0 | < 0.001 |
~ 8.0 | 327 | 40.0 | 719 | 62.6 | < 0.001 |
> 8.0 | 98 | 28.1 | 266 | 40.3 | 0.026 |
Depth of infiltration (pT) | |||||
pT1 | 180 | 91.4 | 2710 | 95.0 | 0.056 |
pT2 | 150 | 71.4 | 547 | 85.0 | 0.001 |
pT3 | 73 | 54.3 | 621 | 75.3 | < 0.001 |
pT4a | 573 | 44.4 | 970 | 47.7 | 0.352 |
pT4b | 129 | 26.1 | 29 | 23.6 | 0.278 |
Nodal status (pN) | |||||
pN0 | 320 | 80.9 | 3111 | 92.8 | < 0.001 |
pN1 | 200 | 61.8 | 583 | 84.1 | < 0.001 |
pN2 | 184 | 60.1 | 493 | 68.9 | 0.020 |
pN3a | 245 | 32.8 | 432 | 45.1 | 0.001 |
pN3b | 156 | 16.8 | 258 | 22.9 | 0.249 |
Distal metastasis (M) | |||||
M0 | 981 | 59.2 | 4748 | 83.0 | < 0.001 |
M1 | 124 | 15.0 | 129 | 21.6 | 0.404 |
Stage | |||||
I | 221 | 91.6 | 2928 | 94.9 | 0.106 |
II | 216 | 67.9 | 772 | 81.2 | 0.001 |
III | 544 | 42.7 | 1048 | 51.6 | 0.001 |
IV | 124 | 15.0 | 129 | 21.6 | 0.404 |
Surgical methods | |||||
Open surgery | 943 | 52.9 | 3675 | 78.1 | < 0.001 |
Minimal invasive surgery | 162 | 62.2 | 1202 | 92.0 | < 0.001 |
Resection type | |||||
Subtotal gastrectomy | 827 | 59.1 | 3606 | 86.1 | <0.001 |
Total gastrectomy | 278 | 40.0 | 1271 | 68.0 | <0.001 |
Lymphadenectomy | |||||
D1/D1+ | 578 | 49.4 | 2278 | 91.3 | < 0.001 |
D2/D2+* | 527 | 59.6 | 2599 | 72.3 | < 0.001 |
Radicality of surgery | |||||
R0 | 996 | 58.6 | 4695 | 83.6 | < 0.001 |
R1/R2 | 109 | 14.4 | 182 | 25.7 | 0.065 |
Chemotherapy | |||||
No | 593 | 50.0 | 3396 | 91.5 | < 0.001 |
Yes | 512 | 59.2 | 1481 | 57.9 | 0.347 |
Abbreviations: OSR, overall survival rate.
D2 included No.14v lymph nodes dissection.
p-value for log-rank test.