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. 2016 May 15;7(28):44660–44675. doi: 10.18632/oncotarget.9378

Table 3. Survival analyses stratified by clinicopathologic characteristics and treatment parameters in different countries.

China (N = 1105) Korea (N = 4877) P value
N 5-y OSR (%) N 5-y OSR (%)
Gender
 Female 324 56.3 1700 83.3 < 0.001
 Male 781 53.4 3177 80.4 < 0.001
Age (yrs)
 < 60 618 55.4 2643 84.5 < 0.001
 ≥ 60 487 52.9 2234 77.6 < 0.001
Longitudinal Tumor location
 Upper third 280 43.7 670 76.9 < 0.001
 Middle third 140 54.4 1334 82.4 < 0.001
 Lower third 661 59.9 2861 82.1 < 0.001
 Whole stomach 24 23.4 12 43.7 0.155
Differentiation
 G1 11 90.0 645 92.0 0.814
 G2 148 62.7 1387 81.0 < 0.001
 G3 946 52.6 2845 79.1 < 0.001
Tumor size (cm)
≤ 2 157 83.8 1660 94.7 < 0.001
~ 5.0 523 59.2 2232 83.0 < 0.001
~ 8.0 327 40.0 719 62.6 < 0.001
> 8.0 98 28.1 266 40.3 0.026
Depth of infiltration (pT)
 pT1 180 91.4 2710 95.0 0.056
 pT2 150 71.4 547 85.0 0.001
 pT3 73 54.3 621 75.3 < 0.001
 pT4a 573 44.4 970 47.7 0.352
 pT4b 129 26.1 29 23.6 0.278
Nodal status (pN)
 pN0 320 80.9 3111 92.8 < 0.001
 pN1 200 61.8 583 84.1 < 0.001
 pN2 184 60.1 493 68.9 0.020
 pN3a 245 32.8 432 45.1 0.001
 pN3b 156 16.8 258 22.9 0.249
Distal metastasis (M)
 M0 981 59.2 4748 83.0 < 0.001
 M1 124 15.0 129 21.6 0.404
Stage
 I 221 91.6 2928 94.9 0.106
 II 216 67.9 772 81.2 0.001
 III 544 42.7 1048 51.6 0.001
 IV 124 15.0 129 21.6 0.404
Surgical methods
 Open surgery 943 52.9 3675 78.1 < 0.001
 Minimal invasive surgery 162 62.2 1202 92.0 < 0.001
Resection type
 Subtotal gastrectomy 827 59.1 3606 86.1 <0.001
 Total gastrectomy 278 40.0 1271 68.0 <0.001
Lymphadenectomy
 D1/D1+ 578 49.4 2278 91.3 < 0.001
 D2/D2+* 527 59.6 2599 72.3 < 0.001
Radicality of surgery
 R0 996 58.6 4695 83.6 < 0.001
 R1/R2 109 14.4 182 25.7 0.065
Chemotherapy
 No 593 50.0 3396 91.5 < 0.001
 Yes 512 59.2 1481 57.9 0.347

Abbreviations: OSR, overall survival rate.

*

D2 included No.14v lymph nodes dissection.

p-value for log-rank test.