Table 5. Acute toxicity.
CTC Grade | PF group (n = 102) | DP group (n = 102) | Pa (PF vs. DP) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | ||
Anemia | 56 | 26 | 13 | 6 | 1 | 55 | 28 | 13 | 5 | 1 | 0.774 |
Leukocytopenia | 21 | 20 | 25 | 16 | 20 | 21 | 19 | 14 | 26 | 22 | 0.088 |
Thrombopenia | 73 | 15 | 10 | 3 | 0 | 65 | 20 | 7 | 8 | 2 | 0.045 |
Gastrointestinal | 37 | 33 | 21 | 15 | 0 | 33 | 41 | 9 | 19 | 0 | 0.574 |
Skin toxicity | 36 | 37 | 22 | 7 | 0 | 29 | 38 | 16 | 19 | 0 | 0.020 |
Esophagitis | 9 | 49 | 28 | 16 | 0 | 13 | 58 | 27 | 4 | 0 | 0.008 |
Pneumonitis | 70 | 21 | 9 | 2 | 0 | 75 | 18 | 6 | 3 | 0 | 0.684 |
P-values were calculated using the chi-squared test to compare patients’ grade 3-4 toxicities between the DP and PF groups.