Table VI.

Candidate EMB genes in Arabidopsis based on sequence similarity to essential genes in other model eukaryotes

Result of Querying Arabidopsis Genome	Query Dataset of Essential Genesa
		Yeast	Worm	Total
Matched Arabidopsis genes found	1,542	1,870	2,362
Not a known indispensable geneb	1,454	1,756	2,225
Top match is not a known indispensable	394	421	636
Unique gene without paralogsc	165	139	244

^aBLASTP comparisons were performed using <e−30 as a significant match. Datasets: 1,009 Saccharomyces (Giaever et al., 2002) and 1,158 Caenorhabditis (Kamath et al., 2003) nonviable genes. Total refers to a nonoverlapping set from yeast and worm combined, with duplicate matches removed.

^bNumber of Arabidopsis genes that represent a significant match to a yeast or worm essential gene but do not correspond to a known Arabidopsis gene with a mutant phenotype.

^cTop Arabidopsis match to a yeast or worm essential; lacks a paralog. None of these corresponds to a known EMB gene.