Figure 1.

CAT activity of hAT1R reporter gene constructs in 25 mM glucose. CAT activity for serially deleted promoter fragments in pCAT vector was determined. (A) Schematic representation of the pCAT reporter expression vector containing serially deleted 5′ promoter region of the hAT1R gene. pCAT-hP1 is labeled with a number of putative transcription binding sites. (B) Solid bars represent the CAT activity for each serially deleted hAT1R promoter fragment in hPTECs. Data are expressed as the mean ± SEM (n = 4–6). ^*p <0.05 versus basic vector pCAT-B.