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. 2016 Dec 20;12:137–149. doi: 10.2147/IJN.S107593

Scheme 2.

Scheme 2

Synthesis of diblock copolymer mPEG-b-P(MMD-co-LA) and cationic copolymer P(MMD-co-LA)-g-PEI.

Abbreviations: mPEG, methoxy-poly(ethylene glycol); P(MMD-co-LA), poly(3(S)-methyl-morpholine-2,5-dione-co-lactide); PEI, polyethylenimine; Sn(Oct)2, stannous octoate; DMAP, 4-dimethylamino pyridine; EDC, 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride; NHS, N-hydroxy succinimide; DMSO, dimethyl sulfoxide.