Table 1.
Parameters of CSD
| n | Propagation velocity (mm/min) | Amplitude (mV)
|
Time to half amplitude (seconds)
|
Number of CSDs/2 hours
|
||||
|---|---|---|---|---|---|---|---|---|
| E1 | E2 | E1 | E2 | E1 | E2 | |||
| Control | 6 | 2.93±0.5 | 25.41±4.7 | 29.04±4.6 | 26.5±12.2 | 27.39±8 | 19.83±6.9 | 15.33±4.1 |
| NTG | 5 | 2.97±0.5 | 24.96±5 | 26.24±6.1 | 24.21±9.1 | 25.07±8.9 | 22.6±7.1 | 22.80±5.7 |
| NTG + Suma | 5 | 2.84±0.3 | 25.87±5.9 | 28.29±6.9 | 28.03±6.1 | 25.54±6.7 | 13.2±4.1 | 13.8±5.9* |
| NTG + SZR-105 | 5 | 2.93±0.7 | 26±5.6 | 28.53±5.1 | 28.5±7.2 | 31.94±8.5 | 22±3.9 | 16.8±2.4 |
| NTG + SZR-109 | 5 | 2.78±0.4 | 26.47±5.2 | 27.95±5.4 | 29.8±8.6 | 29.61±7.4 | 20.6±3.2 | 15.6±2.1 |
Notes:
*
P=0.032 (multiple comparison of NTG groups by Kruskal–Wallis ANOVA); values are mean ± SD.
Abbreviations: CSD, cortical spreading depression; NTG, nitroglycerin; Suma, sumatriptan; ANOVA, analysis of variance; SD, standard deviation.