Figure 2.

Herb-major hub-pathway network.

Notes: Green diamonds represent each herb in YHQFC; round nodes represent putative targets of constituent compounds of YHQFC; nodes marked with red rings represent known therapeutic targets in the treatment of chronic bronchitis. Blue hexagons represent main pathways from enrichment analysis of major targets. Edges represent interactions among herbs, putative targets, and known therapeutic targets for the treatment of chronic bronchitis.

Abbreviations: YHQFC, Yin–Huang–Qing–Fei capsule; SCP, Shi Chang Pu (Acorus tatarinowii Schott); XJYZH, Xin Jiang Yi Zhi Hao (Artemisia rupestris L.); ZS, Zhi Shi (Citrus aurantium L.); CSL, Chuan Shan Long (Dioscorea nipponica Makino); MMH, Mi Ma Huang (Ephedra sinica Stapf); PPY, Pi Pa Ye (Eriobotrya japonica (Thunb.) Lindl.); ZBM, Zhe Bei Mu (Fritillaria thunbergii Miq.); YXY, Yin Xing Ye (Ginkgo biloba L); GC, Gan Cao (Glycyrrhiza uralensis Fisch.); SSG, Sheng Shi Gao (Gypsum Fibrosum); DQY, Da Qing Ye (Isatis indigotica Fort.); BTLZ, Bei Ting Li Zi (Lepidium apetalum Willd.); WWZ, Wu Wei Zi (Schisandra chinensis [Turcz.] Baill.); KXR, Ku Xing Ren (Semen Armeniacae Amarum).