Table 2.
Baseline patient characteristics: overall and by mCOPD medication adherence statusa
| Baseline patient characteristic | Overall (n=14,117) |
Adherent to mCOPD medications (n=2,940) |
Non-adherent to mCOPD medications (n=11,177) |
P-value |
|---|---|---|---|---|
| Age, years | ||||
| Mean (SD) | 69.9 (±9.2) | 69.8 (±8.8) | 70.0 (±9.3) | 0.3402 |
| Median (IQR) | 70.0 (66.0–76.0) | 70.0 (66.0–76.0) | 70.0 (66.0–76.0) | |
| Age category, n (%) | ||||
| 40–49 years | 369 (2.6) | 67 (2.3) | 302 (2.7) | 0.2008 |
| 50–59 years | 1,471 (10.4) | 305 (10.4) | 1,166 (10.4) | 0.9270 |
| 60–69 years | 4,799 (34.0) | 1,022 (34.8) | 3,777 (33.8) | 0.3235 |
| 70–79 years | 5,324 (37.7) | 1,135 (38.6) | 4,189 (37.5) | 0.2620 |
| 80–89 years | 2,154 (15.3) | 411 (14.0) | 1,743 (15.6) | 0.0303 |
| Sex, n (%) | ||||
| Female | 8,348 (59.1) | 1,769 (60.2) | 6,579 (58.9) | 0.1992 |
| Male | 5,769 (40.9) | 1,171 (39.8) | 4,598 (41.1) | |
| Geographic location, n (%) | ||||
| Northeast | 254 (1.8) | 76 (2.6) | 178 (1.6) | 0.0003 |
| Midwest | 3,481 (24.7) | 858 (29.2) | 2,623 (23.5) | <0.0001 |
| South | 9,285 (65.8) | 1,740 (59.2) | 7,545 (67.5) | <0.0001 |
| West | 1,097 (7.8) | 266 (9.0) | 831 (7.4) | 0.0037 |
| Line of business, n (%) | ||||
| Medicare | 13,512 (95.7) | 2,789 (94.9) | 10,723 (95.9) | 0.0105 |
| Commercial | 605 (4.3) | 151 (5.1) | 454 (4.1) | |
| RxRisk-V comorbidity scoreb | ||||
| Mean (SD) | 7.2 (±3.1) | 7.0 (±3.1) | 7.2 (±3.1) | 0.0004 |
| Median (IQR) | 7.0 (5.0–9.0) | 7.0 (5.0–9.0) | 7.0 (5.0–9.0) | |
| Influenza vaccination status, n (%) | ||||
| Nullc | 5,488 (38.9) | 1,042 (35.4) | 4,446 (39.8) | <0.0001 |
| Partialc | 4,434 (31.4) | 957 (32.6) | 3,477 (31.1) | 0.1338 |
| Fullc | 4,195 (29.7) | 941 (32.0) | 3,254 (29.1) | 0.0023 |
Notes:
a
Measured during the 12-month pre-index period.
b
RxRisk-V score without DME ranges from 0 to 42, with a higher score indicating a greater chronic disease burden.
c
Influenza vaccination status was based on the number and timing of vaccine claims during the post-index period as follows: null =0; partial = ≥1; full = ≥2 claims occurring 6 months or greater apart.
Abbreviations: DME, durable medical equipment; IQR, interquartile range; SD, standard deviation; mCOPD, maintenance COPD.